The Science of Sugar Blocker

Cutting back on sugar is an important part of losing weight. Excess sugar adds unneeded calories and contributes to body fat accumulation but the body needs sugar (glucose) to function. 

How the body metabolizes sugar

Shortly after consuming any food or beverage containing sugar or starch, the body reacts by stimulating insulin. Between two to four hours later, insulin clears sugar from the blood and glucose levels fall precipitously. But insulin hangs around, looking for more sugar. This triggers counter-regulatory hormones to kick up your appetite.

This cycle contributes to poor energy, unhealthy cholesterol and fat storage. Fat cells literally “close the door” on the release of fatty acids for use as energy. This up-and-down cycle also starts to fatigue the body’s beta cells, which secrete insulin. Chronic high blood sugar can result if this cycle is continues for too much time.



How does Sugar Blocker do it?

Sugar Blocker was developed as a solution to help reduce the craving for sweets by inhibiting the taste of sugar on the tongue. Sugary foods and beverages no longer offer an appealing taste, which curbs ones appetite to consume them.

The key ingredient in PharmaPure Sugar Blocker is Gymnema Sylvestre. The leaves of this tropical, woody vine have been used in the ancient Indian Ayurvedic medicine for thousands of years. It became known in Western medicine as a “sugar destroyer”1due to its ability to inhibit the action and taste of sugar.(1)(2)

When gymnema is consumed, it interferes with sugar taste receptors in the mouth, thereby disconnecting the chain of hormonal messengers responsible for sugar cravings.(3)(4) Additional research suggests gymnema can also inhibit gastric emptying, delaying or blocking sugar absorption after a meal.(5).

Other key ingredients in Sugar Blocker include:

Chromium (as chromium polynicotinate): Chromium is naturally found in foods such as brewer’s yeast, broccoli, green beans and milk/dairy products. Low chromium levels are associated with glucose intolerance; increasing chromium intake can lead to improved sugar metabolism in individuals with diabetes. Chromium also helps regulate insulin levels: in the presence of chromium, much lower amounts of insulin are required.(5)(6)

Vanadium (as vanadyl sulfate): PharmaPure Sugar Blocker’s third “hero”     
ingredient is vanadyl sulfate. It’s sourced from the mineral vanadium, which is named for the Norse goddess of beauty, Freyja (who was also referred to as Vanadis), because of its beautiful colors


Vanadium is a trace element that naturally occurs in many foods and exhibits insulin-like activity(9). Emerging evidence suggests vanadyl sulfate can promote healthy blood sugar levels and promote healthy insulin production in the liver (10). Vanadyl sulfate has been shown to work synergistically with chromium (10).

Disclaimer: For adults only. Please consult with your physician prior to use if you are currently taking any diabetes medications. If you are pregnant or nursing, consult with your doctor before use.



  1. Tiwari PAhmad KBaig MH. “Gymnema sylvestre for Diabetes: From Traditional Herb to Future's Therapeutic.” Current Pharmaceutical Design. 2017;23(11):1667-1676
  2. Al-Romaiyan ALiu BDocherty RHuang GCAmiel SPersaud SJJones PM. “Investigation of intracellular signaling cascades mediating stimulatory effect of a Gymnema sylvestre extract on insulin secretion from isolated mouse and human islets of Langerhans.” Diabetes, Obesity and Metabolism A Journal of Pharmacology and Therapeutics. 2012 Dec;14(12):1104-13
  3. Sanematsu K, Shingmura N, Ninomiya Y. binding properties between human sweet receptor and sweet-inhibitor, gymnemic acids. Jour Oral Biosci 2017;59:127-130
  4. Hudson SDSims CAOdabasi AZColquhoun TASnyder DJStamps JJDotson SCPuentes LBartoshuk LM. “Flavor Alterations Associated with Miracle Fruit and Gymnema sylvestre.” Chemical Senses. 2018 Aug 24;43(7):481-488
  5. Kashima H, Eguchi K, Miyamoto K et al. Suppression of Oral Sweet taste sensation with Gymnema sylvestre Affects Postprandial Gastrointestinal Blood Flow and Gastric Empyting in Humans. Chemical Senses, 2017;42:295-302
  6. Althuis MD, Jordan NE, Ludington EA, Wittes JT. Glucose and insulin responses to dietary chromium supplements: a meta-analysis. Am J Clin Nutr 2002;76:148-55
  7. Anderson, RA. Essentiality of chromium in humans. Sci. Tot. Environ. 1989;86:75
  8. Lee NA. Reasner CA. “Beneficial effect of chromium supplementation on serum triglyceride levels in NIDDM.” Diabetes Care. 1994;17(12):1449-52 Dec
  9. Nechay BR. Mechanism of action of vanadium. Ann Rev Pharmcol Toxicol 1984;24:501-524
  10. Boden G. Chen X. Ruiz J. van Rossum GD. Turco S. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism: Clinical & Experimental. 1996;45(9):1130-5